Alprazolum|Structure|Mechanism of action|Uses|Side-effects|Alcelam|Alplaz|Esparon|Alpronax|Bestrol|Ralozam|Solanax|Anpress

   

 Alprazolam

It is a benzodiazepine drug that is used in the treatment of panic and anxiety disorder. Alprazolam is a white crystalline powder that is insoluble in water, alcohol, and chloroform. The brand name of alprazolam is Xanax. The molecular weight of alprazolam is 308 gm/mol. The melting point is, 229°C. It is also known as, Alcelam, Alplaz, Esparon, Alpronax, Bestrol, Ralozam, Solanax, Anpress etc.

Structure:

The molecular formula of alprazolam is,[C17H13ClN4].

The IUPAC name of alprazolum is, 8-chloro-1-methyl-6-phenyl-4H-[1,2,4]triazole[4,3a] [1,4] benzodiazepine.

Synthesis:

Mechanism of action:

Alprazolam is a triazolobenzodiazepine that is used in the treatment of anxiety and panic disorder. Benzodiazepine binds with Gama Amino Butyric Acid(GABA) receptors. It enhances the effects of GABA receptors in the body. A chloride ion channel is responsible for the enhancement of GABA-mediated synaptic inhibition and reduced anxiety.

Uses:

It is used in the treatment of anxiety. It is also used in panic disorder. It is not used for the treatment of insomnia.

Side-effects:

The overdose of alprazolam shows different types of side effects like,

1. Dizziness.
2. Tiredness.
3. Drowsiness.
4. Irregular heartbeat
5. Talkativeness.
6. Irritability.
7. Extreme sleepiness.
8. Difficulty in breathing.